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Pioneering live biotherapeutics
in the respiratory tract.
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Publications by Publications
by scientific team
Engineered live bacteria suppress Pseudomonas aeruginosa infection in mouse lung and dissolve endotracheal-tube biofilms
LoxTnSeq: random transposon insertions combined with cre/lox recombination and counterselection to generate large random genome reductions.
Engineering a genome-reduced bacterium to eliminate Staphylococcus aureus biofilms in vivo.
Widespread ribosome stalling in a genome-reduced bacterium and the need for translational quality control.
Functional Characterization of the Cell Division Gene Cluster of the Wall-less Bacterium Mycoplasma genitalium
Lox'd in translation: contradictions in the nomenclature surrounding common lox-site mutants and their implications in experiments
Protein quality control and regulated proteolysis in the genome-reduced organism Mycoplasma pneumoniae
A RAGE Based Strategy for the Genome Engineering of the Human Respiratory Pathogen Mycoplasma pneumoniae.
Immunodominant proteins P1 and P40/P90 from human pathogen Mycoplasma pneumoniae.
FASTQINS and ANUBIS: two bioinformatic tools to explore facts and artifacts in transposon sequencing and essentiality studies.
Mycoplasma pneumoniae Genome Editing Based on Oligo Recombineering and Cas9-Mediated Counterselection
Characterization of different alginate lyases for dissolving Pseudomonas aeruginosa biofilms.
Inferring Active Metabolic Pathways from Proteomics and Essentiality Data.
Impact of C-terminal amino acid composition on protein expression in bacteria.
CReasPy-Cloning: A Method for Simultaneous Cloning and Engineering of Megabase-Sized Genomes in Yeast Using the CRISPR-Cas9 System
Determination of the Gene Regulatory Network of a Genome-Reduced Bacterium Highlights Alternative Regulation Independent of Transcription Factors
SynMyco transposon: engineering transposon vectors for efficient transformation of minimal genomes.
The role of clonal communication and heterogeneity in breast cancer.
Unraveling the hidden universe of small proteins in bacterial genomes
Tuning Gene Activity by Inducible and Targeted Regulation of Gene Expression in Minimal Bacterial Cells
Cryo-electron tomography analyses of terminal organelle mutants suggest the motility mechanism of Mycoplasma genitalium.
Defined chromosome structure in the genome-reduced bacterium Mycoplasma pneumoniae.
Bacterial antisense RNAs are mainly the product of transcriptional noise.
Integration of multi-omics data of a genome-reduced bacterium: Prevalence of post-transcriptional regulation and its correlation with protein abundances
Rescuing discarded spectra: Full comprehensive analysis of a minimal proteome.
Comparative "-omics" in Mycoplasma pneumoniae Clinical Isolates Reveals Key Virulence Factors
Distinguishing between productive and abortive promoters using a random forest classifier in Mycoplasma pneumoniae
Defining a minimal cell: essentiality of small ORFs and ncRNAs in a genome-reduced bacterium
MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae
Assessing the hodgepodge of non-mapped reads in bacterial transcriptomes: real or artifactual RNA chimeras?
In situ overlap and sequence synthesis during DNA assembly
Dissecting the energy metabolism in Mycoplasma pneumoniae through genome-scale metabolic modeling
Comprehensive methylome characterization of Mycoplasma genitalium and Mycoplasma pneumoniae at single-base resolution
Transcription start site associated RNAs in bacteria
A trigger enzyme in Mycoplasma pneumoniae: impact of the glycerophosphodiesterase GlpQ on virulence and gene expression
Bacterial transcriptomics: what is beyond the RNA horiz-ome?
Cell division in a minimal bacterium in the absence of ftsZ
A new promoterless reporter vector reveals antisense transcription in Mycoplasma genitalium
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